Best Healthcare Stocks of 2025 and the April Tariff Crash Recovery stocks in our 2025 Stock Market Review
Happy New Year from YP Investors!
2025 was a solid year for US Stocks as the S&P 500 had over a 16% return despite the large downturn from the April Tariff crash. The climb back from the tariff downturn was led by AI enthusiasm in the Tech Sector.
Today we will look back at the Best and Worst Performing Stocks of 2025. We also look at how the Top Performers of 2024 faired last year.
Below are lists of the top and bottom performing stocks, Current Market Conditions, and Updated Securities lists.
Top Performers of 2025:
The Top Performers of 2025 were all Healthcare companies.
- TOI +1,046.88%
Oncology Institute Inc
Sector: Healthcare
- CDTX +775.37%
Cidara Therapeutics Inc
Sector: Healthcare
- PVLA +735.67%
Palvella Therapeutics Inc
Sector: Healthcare
- CELC +665.80%
Celcuity Inc
Sector: Healthcare
- TERN +625.32%
Terns Pharmaceuticals Inc
Sector: Healthcare
Worst Performers of 2025:
The worst performers of the year were a mix of sectors but the most from Technology.
- ILLR -98.80%
Triller Group Inc
Sector: Technology
- SAFX -97.45%
XCF Global Inc
Sector: Utilities
- ZSPC -96.57%
Zspace Inc
Sector: Technology
- NFE -92.62%
New Fortress Energy Inc
Sector: Energy
- SEAT -92.29%
Vivid Seats Inc
Sector: Communication Services
How did the Top Performers of 2024 do in 2025?:
There were mixed results with the top performers of 2025, so it is tough to draw any conclusions from last year’s top stocks. However only 2/5 ere positive in 2025, so reversion to the mean is a big factor we can see in this collection of stocks.
- TSSI +4,292.59% (2024)
2025: -35.16%
TSS, Inc.
Sector: Technology
- SNYR +3,597.48% (2024)
2025: -54.92%
Synergy CHC Corp.
Sector: Healthcare
- WGS +2,694.91% (2024)
2025: +72.76%
GeneDx Holdings Corp.
Sector: Healthcare
- DRUG +2,418.88% (2024)
2025: +126.42%
Bright Minds Biosciences Inc.
Sector: Healthcare
- KULR +1,818.92% (2024)
2025: -90.34%
KULR Technology Group, Inc.
Sector: Technology
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